Interlobular distribution of hepatic xenobiotic-metabolizing enzyme activities in cattle, goats and sheep.

@article{Wisniewski1987InterlobularDO,
  title={Interlobular distribution of hepatic xenobiotic-metabolizing enzyme activities in cattle, goats and sheep.},
  author={J. A. Wisniewski and David E. Moody and Bruce D Hammock and Lee R. Shull},
  journal={Journal of animal science},
  year={1987},
  volume={64 1},
  pages={210-5}
}
Microsomal and cytosolic enzymes that metabolize xenobiotics were measured in composite samples representing entire livers and in samples from three lobes, using livers of cattle, goats and sheep. Within individual species, concentrations of cytochrome P-450 and b5 and activities of NADPH cytochrome c reductase, aldrin epoxidase, aminopyrine N-demethylase, ethoxycoumarin O-deethylase, microsomal and cytosolic stilbene oxide (epoxide) hydrolase and glutathione S-transferase were not different (P… CONTINUE READING

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