Interlinked mutual inhibitory positive feedbacks induce robust cellular memory effects.

Abstract

Mutual inhibitory positive feedback (MIPF), or double-negative feedback, is a key regulatory motif of cellular memory with the capability of maintaining switched states for transient stimuli. Such MIPFs are found in various biological systems where they are interlinked in many cases despite a single MIPF can still realize such a memory effect. An intriguing… (More)

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Cite this paper

@article{Kim2007InterlinkedMI, title={Interlinked mutual inhibitory positive feedbacks induce robust cellular memory effects.}, author={Tae-Hwan Kim and Sung Hoon Jung and Kwang-Hyun Cho}, journal={FEBS letters}, year={2007}, volume={581 25}, pages={4899-904} }