Interleukin involvement in anterior pituitary cell growth regulation: effects of IL-2 and IL-6.

@article{Arzt1993InterleukinII,
  title={Interleukin involvement in anterior pituitary cell growth regulation: effects of IL-2 and IL-6.},
  author={Eduard Arzt and Rosa Buric and Gil Stelzer and Johanna Stalla and Joachim Sauer and Ulrich Renner and Guenter Karl Stalla},
  journal={Endocrinology},
  year={1993},
  volume={132 1},
  pages={459-67}
}
The pituitary gland plays a central role in the interactions between the immune and neuroendocrine systems. The expression of receptors for interleukin-1 (IL-1), IL-2, and IL-6 and the intrinsic production of these ILs by pituitary cells have been described. Previous studies have focused on the way cytokines influence hormone secretion. We have determined whether, in addition to these effects, ILs could affect pituitary cell proliferation. In GH3 cells, both IL-2 (1-100 U/ml) and IL-6 (10-500 U… CONTINUE READING
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