Interleukin 9: a candidate gene for asthma.

@article{Nicolaides1997Interleukin9A,
  title={Interleukin 9: a candidate gene for asthma.},
  author={Nicholas C. Nicolaides and Kenneth J. Holroyd and Susan L. Ewart and Scott M. Eleff and MichaelD. Kiser and Carl Robert Dragwa and C D Sullivan and Luigi Grasso and Li Yi Zhang and C J Messler and Tianqi Zhou and Steven R. Kleeberger and Kenneth H. Buetow and Roy C Levitt},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1997},
  volume={94 24},
  pages={13175-80}
}
Asthma is a complex heritable inflammatory disorder of the airways associated with clinical signs of atopy and bronchial hyperresponsiveness. Recent studies localized a major gene for asthma to chromosome 5q31-q33 in humans. Thus, this segment of the genome represents a candidate region for genes that determine susceptibility to bronchial hyperresponsiveness and atopy in animal models. Homologs of candidate genes on human chromosome 5q31-q33 are found in four regions in the mouse genome, two on… CONTINUE READING
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Nicolaides et al

  • A. Gessner, H. Blum, +4 authors the open boxes are the exons. Quantification of cloned Sciences
  • Proc. Natl. Acad. Sci. USA 94
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