Interleukin-8 gene expression in middle ear effusions.

  title={Interleukin-8 gene expression in middle ear effusions.},
  author={Keisuke Takeuchi and Keiko Maesako and Atsushi Yuta and Yasuo Sakakura},
  journal={The Annals of otology, rhinology, and laryngology},
  volume={103 5 Pt 1},
Interleukin-8 (IL-8), a monocyte- and macrophage-derived cytokine, displays potent chemotactic-activating properties toward neutrophils, and thus may contribute to the pathogenesis of otitis media with effusion (OME). The objective of this investigation was to demonstrate the expression of the IL-8 gene in middle ear effusion (MEEs) of children and adults with OME. Ribonucleic acids (RNAs) were extracted from MEEs from 16 ears of 13 pediatric patients and 12 ears of 12 adult patients with OME… CONTINUE READING
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