Interleukin-7 and immunologic failure despite treatment with highly active antiretroviral therapy in children perinatally infected with HIV-1.

@article{Chiappini2003Interleukin7AI,
  title={Interleukin-7 and immunologic failure despite treatment with highly active antiretroviral therapy in children perinatally infected with HIV-1.},
  author={Elena Chiappini and L Galli and Chiara Azzari and Maurizio de Martino},
  journal={Journal of acquired immune deficiency syndromes},
  year={2003},
  volume={33 5},
  pages={601-4}
}
Baseline interleukin-7 (IL-7) level has been proposed as a predictor of immunologic response to antiviral therapy, and the use of exogenous IL-7 has been suggested in the treatment of HIV-infected patients. Therefore, we investigated the relationships between IL-7 serum levels and immunologic outcome of highly active antiretroviral therapy (HAART) in 24 children perinatally infected with HIV-1. IL-7 serum levels were evaluated by enzyme-linked immunosorbent assay before switching antiretroviral… CONTINUE READING