Interleukin-6 upregulates the expression of rat luteinizing hormone receptors during granulosa cell differentiation

Interleukin-6 (IL-6) is produced in granulosa cells under normal physiological conditions, including during ovulation. However, the roles of IL-6 in ovarian function, including regulation of LH receptor (LHR) expression in granulosa cells, have not been explored in detail. The aim of this study was to identify the mechanism underlying the effect of IL-6 on… CONTINUE READING