Interleukin 6 trigged ataxia-telangiectasia mutated activation facilitates lung cancer metastasis via MMP-3/MMP-13 up-regulation

Abstract

Our previous studies show that the phosphorylation of ataxia-telangiectasia mutated (ATM) induced by interleukin 6 (IL-6) treatment contributes to multidrug resistance formation in lung cancer cells, but the exact role of ATM activation in IL-6 increased metastasis is still elusive. In the present study, matrix metalloproteinase-3 (MMP-3) and MMP-13 were… (More)
DOI: 10.18632/oncotarget.5825

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Cite this paper

@inproceedings{Jiang2015Interleukin6T, title={Interleukin 6 trigged ataxia-telangiectasia mutated activation facilitates lung cancer metastasis via MMP-3/MMP-13 up-regulation}, author={Yi Na Jiang and Hong Qiong Yan and Xiao Bo Huang and Yi Wang and Qing Li and Feng Gao}, booktitle={Oncotarget}, year={2015} }