Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro.

@article{Hedges1992Interleukin6RO,
  title={Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro.},
  author={Steven Hedges and Markus Svensson and Catharina Svanborg},
  journal={Infection and immunity},
  year={1992},
  volume={60 4},
  pages={
          1295-301
        }
}
This study demonstrated that epithelial cell lines secrete interleukin-6 (IL-6) in response to stimulation with gram-negative bacteria. Human epithelial cell lines of urinary tract origin (A-498 and J82) and of intestinal origin (HT-29 and Caco-2) were analyzed for the secretion of IL-6 by using the B9 bioassay. The supernatants from cells maintained with culture medium were used to assess the constitutive production of IL-6. The supernatants from cells exposed to Escherichia coli strains… CONTINUE READING

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