Interleukin-6 promoter polymorphism and plasma levels in patients with schizophrenia.

@article{Zakharyan2012Interleukin6PP,
  title={Interleukin-6 promoter polymorphism and plasma levels in patients with schizophrenia.},
  author={Roksana Zakharyan and Martin Petrek and Arsen Arakelyan and Frantisek Mrazek and S. A. Atshemyan and Anna S. Boyajyan},
  journal={Tissue antigens},
  year={2012},
  volume={80 2},
  pages={136-42}
}
Schizophrenia is a severe psychiatric disease with inflammatory component. Several studies indicated the increased blood levels of proinflammatory interleukin-6 cytokine in schizophrenia. However, only limited studies explored the relationship between excess production and genetic variations of this cytokine in schizophrenia, and the results were controversial. Here, we investigated possible association of the interleukin-6 gene (IL6) rs1800795 (-174G/C) polymorphism with schizophrenia and… CONTINUE READING