Interleukin 6 induces the expression of vascular endothelial growth factor.

@article{Cohen1996Interleukin6I,
  title={Interleukin 6 induces the expression of vascular endothelial growth factor.},
  author={Tzafra Cohen and Dorit Nahari and L W Cerem and Gera Neufeld and Ben Zion Levi},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 2},
  pages={
          736-41
        }
}
Angiogenesis, the formation of new blood vessels, is induced by various growth factors and cytokines that act either directly or indirectly. Vascular endothelial growth factor (VEGF) is a specific mitogen for vascular endothelial cells and therefore has a central role in physiological events of angiogenesis. Interleukin-6 (IL-6) expression on the other hand is elevated in tissues that undergo active angiogenesis but does not induce proliferation of endothelial cells. We demonstrate using… CONTINUE READING
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