Interleukin-6 in rheumatoid arthritis

@article{Nishimoto2006Interleukin6IR,
  title={Interleukin-6 in rheumatoid arthritis},
  author={N. Nishimoto},
  journal={Current Opinion in Rheumatology},
  year={2006},
  volume={18},
  pages={277–281}
}
  • N. Nishimoto
  • Published 2006
  • Medicine
  • Current Opinion in Rheumatology
  • Purpose of reviewRecent progress in cytokine studies has clarified the pathological roles played by cytokines and provided key evidence that antagonizing their actions can be therapeutic. The pathogenesis of rheumatoid arthritis, an autoimmune inflammatory disease, involves inflammatory cytokines such as tumour necrosis factor-α, interleukin-1 and interleukin-6. Anti-tumour necrosis factor-α and anti-interleukin-1 therapies have been used successfully to treat rheumatoid arthritis, but they are… CONTINUE READING
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    References

    SHOWING 1-10 OF 40 REFERENCES
    Interleukin 6 Is Required for the Development of Collagen-induced Arthritis
    • 599
    • PDF
    Etanercept Therapy in Rheumatoid Arthritis
    • 841
    Interleukin-6 in biology and medicine.
    • 1,307
    Do We Need New Treatment That Goes beyond Tumor Necrosis Factor Blockers for Rheumatoid Arthritis?
    • 38