Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants.

@article{Wu2009Interleukin6GA,
  title={Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants.},
  author={Y. Wayne Wu and Lisa A Croen and Anthony R. Torres and Judy Van de Water and Judith K. Grether and Nathaniel N Hsu},
  journal={Annals of neurology},
  year={2009},
  volume={66 5},
  pages={663-70}
}
OBJECTIVE Chorioamnionitis is associated with increased risk for cerebral palsy (CP) in term infants. A functional polymorphism in the interleukin-6 (IL-6) gene has been implicated in newborn brain injury. We studied whether the IL-6 -174 G/C polymorphism confers increased risk for CP in term infants. METHODS This population-based case-control study included 334,333 live-born infants born at >or=36 weeks gestation within Kaiser Permanente Medical Care Program from 1991 to 2002. Case patients… CONTINUE READING

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