Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation

Abstract

Although it is known that ataxia-telangiectasia mutated (ATM) and interleukin 6 (IL-6) contribute to multiple drug resistance (MDR) in tumor chemotherapy, the exact role of ATM activation in MDR resulting from increased IL-6 expression is still unclear. In the present study, we demonstrate that the activation of the ATM-NF-kappaB pathway, resulting from… (More)
DOI: 10.1111/cas.12478

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@inproceedings{Yan2014Interleukin6A, title={Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation}, author={Hong Qiong Yan and Xiao Bo Huang and Shi Ke and Yi Na Jiang and Yue Zhang and Y{\`i} N. W{\'a}ng and Juan Li and Feng Gao}, booktitle={Cancer science}, year={2014} }