Interleukin-6 and tumor necrosis factor alpha in synovial fluid are associated with progression of radiographic knee osteoarthritis in subjects with previous meniscectomy.

@article{Larsson2015Interleukin6AT,
  title={Interleukin-6 and tumor necrosis factor alpha in synovial fluid are associated with progression of radiographic knee osteoarthritis in subjects with previous meniscectomy.},
  author={Staffan Larsson and Martin Englund and Andr{\'e} Struglics and L Stefan Lohmander},
  journal={Osteoarthritis and cartilage},
  year={2015},
  volume={23 11},
  pages={1906-14}
}
OBJECTIVE To explore potential associations between proinflammatory cytokines in synovial fluid and progression of osteoarthritis (OA) in meniscectomized subjects. DESIGN We studied 132 subjects on average 18 years after meniscectomy, with a second examination 4-10 years later. We measured concentrations of interleukin (IL)-6, -8 and tumor necrosis factor (TNF)-α by multiplex immunoassay, graded radiographic features of tibiofemoral and patellofemoral OA according to the Osteoarthritis… CONTINUE READING
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