Interleukin-6 and chronic inflammation

@inproceedings{Gabay2006Interleukin6AC,
  title={Interleukin-6 and chronic inflammation},
  author={Cem Gabay},
  booktitle={Arthritis research & therapy},
  year={2006}
}
Interleukin (IL)-6 is produced at the site of inflammation and plays a key role in the acute phase response as defined by a variety of clinical and biological features such as the production of acute phase proteins. IL-6 in combination with its soluble receptor sIL-6Ralpha, dictates the transition from acute to chonic inflammation by changing the nature of leucocyte infiltrate (from polymorphonuclear neutrophils to monocyte/macrophages). In addition, IL-6 exerts stimulatory effects on T- and B… CONTINUE READING
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