Interleukin-6: possible biological roles during exercise.

  title={Interleukin-6: possible biological roles during exercise.},
  author={Dace Reihmane and Flemming Dela},
  journal={European journal of sport science},
  volume={14 3},
Interleukin-6 (IL-6) is a multifunctional cytokine that exerts its modulatory effects on cells that express membrane bound IL-6 receptors; however, IL-6 in a complex with soluble IL-6R can bind to any cell that express glycoprotein 130 (gp130). Thus, all cell types may respond to the pro- as well as anti-inflammatory properties of IL-6. Since the first report of acute exercise-induced increase in plasma IL-6 in the early 1990s, scientists have tried to elucidate the factors that influence the… CONTINUE READING
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