Interleukin-6, high sensitivity C-reactive protein, and the development of type 2 diabetes among HIV-positive patients taking antiretroviral therapy.

@article{Dooko2014Interleukin6HS,
  title={Interleukin-6, high sensitivity C-reactive protein, and the development of type 2 diabetes among HIV-positive patients taking antiretroviral therapy.},
  author={Claude B{\'e}t{\'e}n{\'e} A Dooko and St{\'e}phane De Wit and Jacqueline A Neuhaus and Adrian Palfreeman and Rosalie Pepe and James S. Pankow and James D. Neaton},
  journal={Journal of acquired immune deficiency syndromes},
  year={2014},
  volume={67 5},
  pages={538-46}
}
BACKGROUND HIV infection is associated with increased levels of inflammatory markers. Inflammation is hypothesized to play a role in the development of type 2 diabetes. Data addressing this issue among HIV-positive participants are limited. METHODS A cohort of 3695 participants without diabetes, taking antiretroviral therapy and with an average CD4⁺ count of 523 cells/mm³, were followed for an average of 4.6 years. Diabetes risk associated with baseline levels of high sensitivity C-reactive… CONTINUE READING
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