Interleukin 4 receptor expression and growth inhibition of gastric carcinoma cells by interleukin 4.

@article{Morisaki1992Interleukin4R,
  title={Interleukin 4 receptor expression and growth inhibition of gastric carcinoma cells by interleukin 4.},
  author={Takashi Morisaki and Dale Yuzuki and Raymond T.P. Lin and Leland J. Foshag and DonaldL. Morton and Dave S B Hoon},
  journal={Cancer research},
  year={1992},
  volume={52 21},
  pages={
          6059-65
        }
}
The expression of the interleukin 4 (IL-4) receptor (IL-4R) and effects of human recombinant IL-4 on human gastric carcinoma cell lines were studied. We demonstrated that IL-4 inhibited the growth of gastric carcinoma cells in a dose dependent manner (0.1-100 units/ml) in a [3H]thymidine incorporation proliferation assay. The gastric carcinoma cells varied in sensitivity to treatment with low dose IL-4. Treatment of cells with IL-4 altered the morphology of the cells to a "flattened… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 26 CITATIONS

Similar Papers

Loading similar papers…