Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer

@article{Ge2016Interleukin37ST,
  title={Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer},
  author={Guanqun Ge and Aiqin Wang and Jingyue Yang and Yan Chen and Jin Yang and Yize Li and Yan Xue},
  journal={Journal of Experimental & Clinical Cancer Research},
  year={2016},
  volume={35},
  pages={1-10}
}
BackgroundInterleukin-37 (IL-37), a newly identified member of the IL-1 family, has been known to play an immunosuppressive role in a variety of inflammatory disorders, but whether it participates in the regulation of pathogenesis of non-small cell lung cancer (NSCLC) has not been investigated.MethodsReal-time polymerase chain reaction (PCR), western blotting, and immunohistochemical staining were employed to detect IL-37 expression in NSCLC tissues and corresponding adjacent tissues. The… CONTINUE READING
BETA
1
Twitter Mention

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

Reviews of Interleukin-37: Functions, Receptors, and Roles in Diseases

  • BioMed research international
  • 2018
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Mammalian Eps15 homology domain 1 potentiates angiogenesis of non-small cell lung cancer by regulating β2AR signaling

  • Journal of experimental & clinical cancer research : CR
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

IL-37 impairs host resistance to Listeria infection by suppressing macrophage function.

  • Biochemical and biophysical research communications
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 34 REFERENCES

Similar Papers

Loading similar papers…