Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer.

@article{Ge2016Interleukin37ST,
  title={Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer.},
  author={Guanqun Ge and Aiqin Wang and Jingyue Yang and Yan Chen and Jin Yang and Yize Li and Yan Xue},
  journal={Journal of experimental & clinical cancer research : CR},
  year={2016},
  volume={35},
  pages={
          13
        }
}
BACKGROUND Interleukin-37 (IL-37), a newly identified member of the IL-1 family, has been known to play an immunosuppressive role in a variety of inflammatory disorders, but whether it participates in the regulation of pathogenesis of non-small cell lung cancer (NSCLC) has not been investigated. METHODS Real-time polymerase chain reaction (PCR), western blotting, and immunohistochemical staining were employed to detect IL-37 expression in NSCLC tissues and corresponding adjacent tissues. The… CONTINUE READING
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