Interleukin-35: a Potential Therapeutic Agent for Autoimmune Diseases

  title={Interleukin-35: a Potential Therapeutic Agent for Autoimmune Diseases},
  author={Shi-Yang Guan and Rui-xue Leng and Muhammad Imran Khan and Humera Qureshi and Xiang-Pei Li and Dong-qing Ye and Hai-Feng Pan},
Autoimmune diseases contain a large number of pathologies characterized by various factors that contribute to a breakdown in self-tolerance. Cytokine-mediated immunity plays an essential role in the pathogenesis of varieties of autoimmune diseases. Recent studies reveal that interleukin-35 (IL-35), a newly identified cytokine of IL-12 family, is implicated in the pathogenesis of autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc… CONTINUE READING
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