Interleukin-33 levels are elevated in chronic allograft dysfunction of kidney transplant recipients and promotes epithelial to mesenchymal transition of human kidney (HK-2) cells.

@article{Xu2018Interleukin33LA,
  title={Interleukin-33 levels are elevated in chronic allograft dysfunction of kidney transplant recipients and promotes epithelial to mesenchymal transition of human kidney (HK-2) cells.},
  author={Zhen Xu and Chunchun Zhao and Zijie Wang and Jun Tao and Zhijian Han and Wei Zhang and Ruoyun Tan and Min Gu},
  journal={Gene},
  year={2018},
  volume={644},
  pages={113-121}
}
This study is aimed to investigate the potential role of interleukin (IL)-33 in transplanted kidney interstitial fibrosis and the associated mechanism. Serum IL-33 levels were detected using an enzyme-linked immunosorbent assay (ELISA) in healthy volunteers, stable kidney transplantation recipients (KTRs) (stable), KTRs with acute rejection (AR), and KTRs with chronic allograft dysfunction (CAD) (CAD). Immunohistochemical (IHC) staining, Western blotting, and quantitative real-time PCR (qRT-PCR… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 34 references

Cellular and molecular mechanisms in kidney fibrosis.

The Journal of clinical investigation • 2014
View 2 Excerpts
Highly Influenced

Renal interstitial fibrosis: mechanisms and evaluation.

Current opinion in nephrology and hypertension • 2012
View 3 Excerpts
Highly Influenced

Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation

International journal of biological sciences • 2011
View 2 Excerpts
Highly Influenced

IL33 and kidney disease

F Yang
(review). Mol. Med. Rep • 2016

Upregulation of Interleukin-33 in obstructive renal injury.

Biochemical and biophysical research communications • 2016

Advanced glycation end products accelerate arteriosclerosis after renal transplantation through the AGE/RAGE/ILK pathway

X Liu
Exp. Mol. Pathol • 2015

Similar Papers

Loading similar papers…