Interleukin-32β stimulates migration of MDA-MB-231 and MCF-7cells via the VEGF-STAT3 signaling pathway

  title={Interleukin-32β stimulates migration of MDA-MB-231 and MCF-7cells via the VEGF-STAT3 signaling pathway},
  author={Jeong Su Park and Su Yun Choi and Jeong-hyung Lee and Maria Lee and Eun Sook Nam and Ae Lee Jeong and Sunyi Lee and Sora Y Han and M. -C. Lee and Jong-Seok Lim and Do-Young Yoon and Yongil Kwon and Young Yang},
  journal={Cellular Oncology},
IL-32 is known to play an important role in inflammatory and autoimmune disease responses. In addition to its role in these responses, IL-32 and its different isoforms have in recent years been implicated in the development of various cancers. As of yet, the role of IL-32 in breast cancer has remained largely unknown. By performing immunohistochemical assays on primary breast cancer samples, we found that the level of IL-32β expression was positively correlated with tumor size, number of lymph… CONTINUE READING
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