Interleukin-32, not reduced by salmeterol/fluticasone propionate in smokers with chronic obstructive pulmonary disease.

@article{Du2014Interleukin32NR,
  title={Interleukin-32, not reduced by salmeterol/fluticasone propionate in smokers with chronic obstructive pulmonary disease.},
  author={Yipeng Du and Wei Wang and Wei Yang and Bei He},
  journal={Chinese medical journal},
  year={2014},
  volume={127 9},
  pages={1613-8}
}
BACKGROUND The interleukin (IL)-32/tumor necrosis factor (TNF) a pathway is supposed to play a key role in the amplification of the immune response in chronic obstructive pulmonary disease (COPD) inflammation. Inhaled corticosteroids (ICS) in combination with long-acting β2-agonists (LABA) have shown airway anti-inflammatory effects in recent studies, but the mechanism is still uncertain. METHODS Patients were treated in a randomized, open-labeled, parallel group clinical trial with either a… CONTINUE READING