Interleukin 3 promotes histamine synthesis in hematopoietic progenitors by increasing histidine decarboxylase mRNA expression.

Abstract

Interleukin 3 (IL-3) is a potent stimulator of histamine production by cells from murine hematopoietic organs. We demonstrate herein that this phenomenon results from increased histidine decarboxylase (HDC: EC 4.1.1.22) activity in progenitor-enriched bone marrow cells (around 5% of the total bone marrow) isolated from the low density layers of a… (More)

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@article{Dy1993Interleukin3P, title={Interleukin 3 promotes histamine synthesis in hematopoietic progenitors by increasing histidine decarboxylase mRNA expression.}, author={Mary A V Dy and François Machavoine and Bernard Lebel and Ayumi Ichikawa and Louis No{\"e}l Gastinel and E. Schneider}, journal={Biochemical and biophysical research communications}, year={1993}, volume={192 1}, pages={167-73} }