Interleukin-3, GM-CSF, and G-CSF receptor expression on cell lines and primary leukemia cells: receptor heterogeneity and relationship to growth factor responsiveness.

@article{Park1989Interleukin3GA,
  title={Interleukin-3, GM-CSF, and G-CSF receptor expression on cell lines and primary leukemia cells: receptor heterogeneity and relationship to growth factor responsiveness.},
  author={Linda S. Park and Peter E Waldron and Daniel Friend and Helmut M. Sassenfeld and Valerie Price and Dirk Anderson and David Cosman and R. Andrews and Irwin D Bernstein and David L. Urdal},
  journal={Blood},
  year={1989},
  volume={74 1},
  pages={56-65}
}
Recombinant human granulocyte-macrophage (GM) colony-stimulating factor (GM-CSF), G-CSF, and interleukin-3 (IL-3) labeled with 125I were used to study the characteristics and distribution of receptors for these factors on in vitro cell lines and on cells from patients with acute nonlymphocytic leukemia (ANL) and acute lymphocytic leukemia (ALL). Receptors for GM-CSF and G-CSF were restricted to a subset of myelomonocytic cell lines whereas IL-3 receptors were also found on pre-B- or early B… CONTINUE READING

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