Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseases.

@article{Levillayer2007Interleukin2I,
  title={Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseases.},
  author={Florence Levillayer and Magali Mas and Fabienne L{\'e}vi-Acobas and Michel Brahic and Jenny FitzGerald Bureau},
  journal={Genetics},
  year={2007},
  volume={176 3},
  pages={1835-44}
}
After intracerebral inoculation, Theiler's virus induces in its natural host, the mouse, an acute encephalomyelitis followed, in susceptible animals, by chronic inflammation and primary demyelination. Susceptibility to demyelination among strains of laboratory mice is explained by the capacity of the immune system to control viral load during persistence. Also, differences of susceptibility to viral load between the susceptible SJL strain and the resistant B10.S strain are mainly due to two… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 19 references

The genetics of the persistent infection and demyelinating disease caused by Theiler ’ s virus

  • J.-F. ureau, X. M ontagutelli, S. L efebvre, J.-L. G uénet, M. P la
  • Annu . Rev . Microbiol .
  • 2005

The role of IL - 12 , IL - 23 and IFN - gamma in immunity to viruses

  • S. D. M iller
  • Cytokine Growth Factor Rev .
  • 2004

pression and regulation of IL - 22 in the IL - 17 - producing CD 4 1 T lymphocytes

  • C. S. D avid P. D. M urray
  • Cell Res .
  • 1999

Similar Papers

Loading similar papers…