Interleukin-21 expanded NKDC in vitro reduces the B16F10 tumor growth in vivo.

@article{Souza2013Interleukin21EN,
  title={Interleukin-21 expanded NKDC in vitro reduces the B16F10 tumor growth in vivo.},
  author={Ana Paula Souza and Cristina Bonorino and St{\'e}fanie P Muraro and L{\'i}lian Cataldi Rodrigues},
  journal={Cytokine},
  year={2013},
  volume={61 1},
  pages={154-60}
}
Innate immunity to tumors is mediated mainly by natural killer cells (NKs) and dendritic cells (DCs). The function of these cells is coordinated by cytokines produced during the inflammatory process. NK cells are highly active against tumors, being an important source of IFN-γ. Natural killer dendritic cells (NKDCs) were recently identified as a group of hybrid cells; some studies claim that they have lytic activity, produce IFN-γ and can also stimulate antigen-specific T cells. Interleukin 21… CONTINUE READING

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