Interleukin 2 treatment of Staphylococcus aureus mastitis.

  title={Interleukin 2 treatment of Staphylococcus aureus mastitis.},
  author={Prasad G Reddy and Dr. M. N. Reddy and S E Pruiett and Mark J. Daley and J. E. J. Shirley and Muckatira M. Chengappa and Frank Blecha},
  volume={4 3},
A study was conducted in dairy cows to evaluate the efficacy of recombinant bovine interleukin 2 (rBoIL-2) as an adjunct to antibiotic therapy in Staphylococcus aureus mastitis. In normal, non-mastitic cows, intramammary infusion of rBoIL-2 caused a tenfold increase in somatic cell counts (SCC) in milk. Co-administration of 2 mg of rBoIL-2 and sodium cephapirin in cows with established S. aureus mastitis decreased SCC and shedding of S. aureus compared with values from cows that were given only… CONTINUE READING