Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells.

  title={Interleukin-2 receptor (Tac antigen) expressed on adult T cell leukemia cells.},
  author={Takashi Uchiyama and Toshiyuki Hori and Mitsuru Tsudo and Yuji Wano and Hiroshi Umadome and S Tamori and Junji Yodoi and Michiyuki Maeda and Hiroyasu Sawami and Haruto Uchino},
  journal={The Journal of clinical investigation},
  volume={76 2},
We studied the expression of the interleukin-2 (IL-2) receptor and the proliferative response to exogenous IL-2 of peripheral blood leukemic cells from patients with adult T cell leukemia (ATL) in order to see whether IL-2 receptor expressed on ATL cells is different from normal IL-2 receptor and whether it plays a role in the neoplastic growth in ATL. Peripheral blood leukemic cells from 42 patients with ATL examined expressed IL-2 receptors that were detected by anti-Tac monoclonal antibody… CONTINUE READING


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