Interleukin-2 inhibits growth of fibroblasts derived from human bone marrow.

@article{Macdonald1990Interleukin2IG,
  title={Interleukin-2 inhibits growth of fibroblasts derived from human bone marrow.},
  author={Donald H. C. Macdonald and James Anthony Adams and Donna Marie McCarthy and Austin John Barrett},
  journal={Acta haematologica},
  year={1990},
  volume={83 1},
  pages={
          26-30
        }
}
The adherent layer that forms in human bone marrow suspension cultures contains fibroblast colonies which arise from colony-forming cells (CFU-F). We have demonstrated that recombinant interleukin-2 (r-IL2) inhibits growth of CFU-F by preventing their entry into S phase. This inhibition is not mediated by gamma-interferon, nor by T lymphocytes, and can be abrogated by anti-IL2 receptor antibody. r-IL2 may influence haematopoiesis by its effect on bone marrow CFU-F. 
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