Interleukin 2 infusion induces haemopoietic growth factors and modifies marrow regeneration after chemotherapy or autologous marrow transplantation.

@article{Heslop1991Interleukin2I,
  title={Interleukin 2 infusion induces haemopoietic growth factors and modifies marrow regeneration after chemotherapy or autologous marrow transplantation.},
  author={Helen E Heslop and Andrew S. Duncombe and Joyce E. Reittie and Concha Bello-Fern{\'a}ndez and Daniel J. Gottlieb and Hugh Grant Prentice and Atul Kumar Mehta and Allan Victor Hoffbrand and Michelle Klein Brenner},
  journal={British journal of haematology},
  year={1991},
  volume={77 2},
  pages={
          237-44
        }
}
Administration of interleukin 2 (IL2) to patients with minimal residual malignant disease following myeloablative chemo-radiotherapy may augment immune reconstitution and reduce the risk of relapse by increasing cytotoxic effector function and cytokine dependent killing directed at residual malignant cells. The ability of IL2 generated activated killer cells to inhibit haemopoietic progenitor cells and to release gamma-interferon (gamma IFN) and tumour necrosis factor (TNF) may, however, retard… CONTINUE READING
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