Interleukin-1beta induces macrophage inflammatory protein-1beta expression in human hepatocytes.

@article{Zhang2003Interleukin1betaIM,
  title={Interleukin-1beta induces macrophage inflammatory protein-1beta expression in human hepatocytes.},
  author={Ting Zhang and Chang-Jiang Guo and Yuan Li and Steven D. Douglas and Xiao-Xue Qi and Li Song and Wen-zhe Ho},
  journal={Cellular immunology},
  year={2003},
  volume={226 1},
  pages={45-53}
}
The investigation of factors that regulate expression of CC-chemokines, the important mediators in immune responses and inflammation processes, has an important significance in understanding the immunopathogenesis of liver diseases. We examined the role of interleukin-1beta (IL-1beta), a multifunctional cytokine, in regulating the expression of macrophage inflammatory protein (MIP)-1beta in human hepatocytes (Huh7 and HepG2). IL-1beta significantly enhanced MIP-1beta expression in these cells… CONTINUE READING