Interleukin-1beta and tumor necrosis factor-alpha in children with major depressive disorder or dysthymia.

@article{Brambilla2004Interleukin1betaAT,
  title={Interleukin-1beta and tumor necrosis factor-alpha in children with major depressive disorder or dysthymia.},
  author={Francesca Brambilla and Palmiero Monteleone and Mario Maj},
  journal={Journal of affective disorders},
  year={2004},
  volume={78 3},
  pages={273-7}
}
BACKGROUND Immune function is altered in adult depressed patients. The aim of our study was to see whether or not cytokine secretion is impaired at a very young phase of development of depressive disorders, possibly being pathogenetically involved in their course. METHODS Basal plasma concentrations of interleukin-1beta (Il-1beta) and tumor necrosis factor-alpha (TNF-alpha) were measured radioimmunologically in 22 drug-free children-adolescents, 11 with recurrent major depressive disorders… CONTINUE READING

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