Interleukin-1beta and insulin elicit different neuroendocrine responses to hypoglycemia.

@article{Ota2009Interleukin1betaAI,
  title={Interleukin-1beta and insulin elicit different neuroendocrine responses to hypoglycemia.},
  author={Kazuki Ota and Johannes Wildmann and Taeko Ota and Hugo Oscar Besedovsky and Adriana del Rey},
  journal={Annals of the New York Academy of Sciences},
  year={2009},
  volume={1153},
  pages={82-8}
}
Interleukin (IL)-1beta induces a prolonged hypoglycemia in mice that is not caused by a reduction in food intake and is dissociable from insulin effects. There is a peripheral component in the hypoglycemia that the cytokine induces resulting from an increased glucose uptake, an effect that can be exerted in a paracrine fashion at the site where IL-1 is… CONTINUE READING