Interleukin 18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells.

@article{Ohtsuki1997Interleukin1E,
  title={Interleukin 18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells.},
  author={Tetsuya Ohtsuki and Mark J. Micallef and Keizo Kohno and Tadao Tanimoto and Masao Ikeda and Masashi Kurimoto},
  journal={Anticancer research},
  year={1997},
  volume={17 5A},
  pages={3253-8}
}
Interleukin-18 (IL-18) induces apoptosis in human myelomonocytic KG-1 cells as determined by agarose gel electrophoresis, and flow cytometry after propidium iodide (PI) staining. Apoptosis was detected 20 hours from the start of culture at concentrations of 100 ng/ml of the cytokine. Although IL-18 induces the production of large amounts of interferon gamma… CONTINUE READING