author={François Fossiez and Jacques Banchereau and Richard C. Murray and Cees van Kooten and Pierre Garrone and Serge J. Lebecque},
  journal={International reviews of immunology},
  volume={16 5-6},
The particular interest of IL-17, a homodimeric cytokine of about 32 kDa, is the strict requirement for an activation signal to induce its expression from a rather restricted set of cells, human memory T cells or mouse alpha beta TCR+CD4-CD8- thymocytes. In contrast with the tightly controlled expression pattern of this gene, the IL-17 receptor, a novel cytokine receptor, is ubiquitously distributed but apparently more abundant in spleen and kidney. In addition to its capture by the T… CONTINUE READING