Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis

@article{Matusevicius1999Interleukin17ME,
  title={Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis},
  author={Darius Matusevicius and Pia Kivis{\"a}kk and Bing He and Nikolaos Kostulas and Volkan {\"O}zenci and Sten Fredrikson and Hans Link},
  journal={Multiple Sclerosis},
  year={1999},
  volume={5},
  pages={101 - 104}
}
Myelin-directed autoimmunity is considered to play a key role in the pathogenesis of multiple sclerosis (MS). Increased production of both pro- and anti-inflammatory cytokines is a common finding in MS. Interleukin-17 (IL-17) is a recently described cytokine produced in humans almost exclusively by activated memory T cells, which can induce the production of proinflammatory cytokines and chemokines from parenchymal cells and macrophages. In situ hybridisation with synthetic oligonucleotide… 
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