Interleukin-17 levels correlate with poor prognosis and vascular endothelial growth factor concentration in the serum of patients with non-small cell lung cancer.

@article{Pan2015Interleukin17LC,
  title={Interleukin-17 levels correlate with poor prognosis and vascular endothelial growth factor concentration in the serum of patients with non-small cell lung cancer.},
  author={Bo Pan and Dehai Che and Jingyan Cao and Jing Shen and Shi Jin and Yongxu Zhou and Fang Liu and Kuo Gu and Yingchun Man and Lihua Shang and Yan Yu},
  journal={Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals},
  year={2015},
  volume={20 4},
  pages={232-9}
}
OBJECTIVE The aim of this study was to explore the clinical role of serum interleukin-17 in patients with non-small-cell lung cancer (NSCLC). MATERIALS AND METHOD IL-17 expression and microvessel density (MVD) were measured via immunohistochemistry in 58 NSCLC tissues. Serum IL-17 and VEGF levels in NSCLC patients (n = 43) and healthy controls (n = 37) were analyzed via enzyme-linked immunosorbent assay. RESULTS Serum IL-17 was elevated and the levels positively correlated with VEGF… CONTINUE READING
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