Interleukin-17 induces src/MAPK cascades activation in human renal epithelial cells.

@article{Hsieh2002Interleukin17IS,
  title={Interleukin-17 induces src/MAPK cascades activation in human renal epithelial cells.},
  author={Hsian-Guey Hsieh and Che-Chang Loong and C. -T. Lin},
  journal={Cytokine},
  year={2002},
  volume={19 4},
  pages={159-74}
}
Interleukin-17 (IL-17) is a T cell derived pro-inflammatory cytokine exhibiting multiple biological activities in a variety of cells. In our previous study, we found that IL-17 expressed early on borderline change of renal allograft rejection by Banff classification both in rat renal allograft model and human renal specimens. Renal epithelial cells (RECs) are the important targets in renal allograft rejection. The purpose of this study was to explore the signalling pathways by which human… CONTINUE READING

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