Interleukin 17 gene polymorphism is associated with anti-aquaporin 4 antibody-positive neuromyelitis optica in the Southern Han Chinese — A case control study

@article{Wang2012Interleukin1G,
  title={Interleukin 17 gene polymorphism is associated with anti-aquaporin 4 antibody-positive neuromyelitis optica in the Southern Han Chinese — A case control study},
  author={Honghao Wang and Xiaonan Zhong and Kai Wang and Wei Qiu and Xueqiang Hu},
  journal={Journal of the Neurological Sciences},
  year={2012},
  volume={314},
  pages={26-28}
}
BACKGROUND Interleukin 17 (IL-17) plays an important role in many autoimmune diseases including neuromyelitis optica (NMO) and multiple sclerosis (MS), which are inflammatory demyelinating diseases of the central nervous system. A large number of non-HLA single nucleotide polymorphisms have been reported to increase the risk of MS. However, their effects on NMO have been less well studied. METHODS Fifty-two anti-aquaporin 4 antibody-positive NMO patients, 69 anti-aquaporin 4 antibody-negative… CONTINUE READING
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