Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis.

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction and bone resorption. The proinflammatory cytokine interleukin 17 (IL-17), primarily produced by Th17 cells, has been shown to be involved in all stages of the disease and to be an important contributor of RA chronicity. Three major processes drive the IL-17-mediated… (More)
DOI: 10.1002/eji.201344184

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