Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells


Pancreatic ductal adenocarcinoma (PDAC) is the 4th leading cause of cancer-related death in Western countries with a 5-year survival rate below 5%. One of the hallmarks of this cancer is the strong desmoplastic reaction within the tumor microenvironment (TME), orchestrated by activated pancreatic stellate cells (PSC). This results in a functional and… (More)
DOI: 10.18632/oncotarget.18185


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