Interleukin 15 activity in the rectal mucosa of inflammatory bowel disease.

@article{Sakai1998Interleukin1A,
  title={Interleukin 15 activity in the rectal mucosa of inflammatory bowel disease.},
  author={Tetsuo Sakai and Kazuo Kusugami and Hirokatsu Nishimura and Takafumi Ando and Taiji Yamaguchi and M Ohsuga and Kenji Ina and Akiko Enomoto and Yukino Kimura and Yasunobu Yoshikai},
  journal={Gastroenterology},
  year={1998},
  volume={114 6},
  pages={1237-43}
}
BACKGROUND & AIMS Interleukin (IL)-15 has been found to share many immunoregulatory activities in lymphocytes with IL-2. The aim of this study was to investigate IL-15 activity in organ cultures, localization of IL-15 messenger RNA (mRNA), and proliferation of lamina propria mononuclear cells (LPMCs) in response to recombinant IL-15 using the mucosal tissues obtained from patients with inflammatory bowel disease (IBD). METHODS The contents of IL-15, tumor necrosis factor alpha, and IL-2 in… CONTINUE READING