Interleukin 13 receptors as biochemical markers in atopic patients.

  title={Interleukin 13 receptors as biochemical markers in atopic patients.},
  author={Yousri Mostafa Hussein and Akhwand Shakeel Ahmad and Mohamed M. Ibrahem and H M Elsherbeny and Sally M. Shalaby and Amal S El-Shal and Norhan Abdalla Sabbah},
  journal={Journal of investigational allergology & clinical immunology},
  volume={21 2},
BACKGROUND Interleukin (IL) 13, a type 2 helper T cell (T(H)2), is an important regulator of inflammatory immune responses. It mediates its action through a receptor complex consisting of IL-13Ralpha1 and IL-4Ralpha. IL-13Ralpha2 binds IL-13 with high affinity and is thought to act primarily as a decoy receptor, sequestering IL-13 and thus inhibiting its… CONTINUE READING