Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

Abstract

Atherosclerotic lesions are characterized by the accumulation of oxidized LDL (OxLDL) and the infiltration of macrophages and T cells. Cytokine expression in the microenvironment of evolving lesions can profoundly contribute to plaque development. While the pro-atherogenic effect of T helper (Th) 1 cytokines, such as IFN-γ, is well established, the role of… (More)
DOI: 10.1002/emmm.201201374

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Cite this paper

@inproceedings{CardiloReis2012Interleukin13PF, title={Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype}, author={Larissa Cardilo-Reis and Sabrina Gruber and Sabine Maria Schreier and Maik D Drechsler and Nikolina Papac-Milicevic and Christian Weber and Oswald Wagner and Herbert Stangl and Oliver Soehnlein and Christoph J. Binder}, booktitle={EMBO molecular medicine}, year={2012} }