Interleukin-13 as an important cytokine: A review on its roles in some human diseases.

@article{Seyfizadeh2015Interleukin13AA,
  title={Interleukin-13 as an important cytokine: A review on its roles in some human diseases.},
  author={Narges Seyfizadeh and Nayer Seyfizadeh and Tohid Gharibi and Zohreh Babaloo},
  journal={Acta microbiologica et immunologica Hungarica},
  year={2015},
  volume={62 4},
  pages={341-78}
}
Interleukin-13 (IL-13) as a pleiotropic cytokine acts through the IL-13Ra1/IL-4Ra complex to induce activation responses which contribute to the inflammatory diseases. Genetic polymorphisms in IL-13 and its receptor components have been proved to be associated with higher disease prevalence rates. Animal models such as in IL-13 deficient mice and transgenic… CONTINUE READING