Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells.

@article{Zurawski1994Interleukin1A,
  title={Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells.},
  author={Gerard Zurawski and Jan de Vries},
  journal={Immunology today},
  year={1994},
  volume={15 1},
  pages={19-26}
}
Interleukin 13 (IL-13) is a recently described protein secreted by activated T cells which is a potent in vitro modulator of human monocyte and B-cell functions. The data, reviewed here by Gerard Zurawski and Jan de Vries, shows that IL-13 shares biological activities with IL-4, their genes are closely linked in both the human and mouse genomes, and there is sequence homology between IL-13 and IL-4 proteins. Although the cloned IL-4 receptor protein (IL-4R) does not bind IL-13, it appears that… CONTINUE READING
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