Interleukin-10 is an independent biomarker of severe traumatic brain injury prognosis.

@article{Soares2012Interleukin10IA,
  title={Interleukin-10 is an independent biomarker of severe traumatic brain injury prognosis.},
  author={Fl{\'a}via Mahatma Schneider Soares and Nicole Menezes de Souza and Marcelo Lib{\'o}rio Schwarzbold and Alexandre Paim Diaz and Jean Costa Nunes and Alexandre Hohl and Priscilla Nunes Abreu da Silva and Juliana Villela Vieira and Rafael Lisboa de Souza and Melina Mor{\'e} Bertotti and Rui Daniel Schoder Prediger and Marcelo Neves Linhares and Andr{\'e} B{\'a}fica and Roger Walz},
  journal={Neuroimmunomodulation},
  year={2012},
  volume={19 6},
  pages={377-85}
}
BACKGROUND Cytokines have been shown to be involved in traumatic brain injury (TBI). We investigated the independent association between serum levels of IL-10 and TNF-α and hospital mortality of patients with severe TBI. METHODS Serum IL-10 and TNF-α levels were determined after a median period (interquartile range (IQ) 25-75) of 10 h (IQ 5-18) after severe TBI in 93 consecutive patients and in randomly selected patients with mild (n = 18) and moderate (n = 16) TBI. In patients with severe… CONTINUE READING
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